Abstract

A bandage is a standard of biomaterial used on wounds to protect from infections and to cure wounds. The adhesive bandage also known as sticking plaster protects the wound from friction, bacteria, damage, and dirt. In this study, the leaf extracts of plant (Chromolaena odorata) coated on textiles are being used as a potential drug to promote wound healing. The phytochemical screening and antimicrobial activities of the ethanolic plant leaf extracts was carried out. The leaf extracts were coated on non-woven viscose rayon fabric using Pad-dry cure method. The physical and biological parameters of the coated fabric were analyzed to determine the process of wound healing. The parameters of pH and absorbency were evaluated using the standard protocols obtained from medical textiles. The antimicrobial efficiency (standard protocol AATCC 100), cytotoxicity (MTT assay) and in vitro scratch wound assay using cell lines was studied. The results showed that developed herbal coated bio-bandage featured all the characteristics for ideal dressing. Therefore, it can be promoted as novel bio-bandage for the healing of wounds.

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