Abstract
A cosmetic product consists of natural or synthetic substances, the purpose of which is to wash, scent, correct and protect the various parts of the human body. Human skin has pores that connect to the oil glands, which produce sebum, an oily liquid that carries dead cells through the hair follicles to the surface of the epidermis, causing the appearance of skin lesions and the growth of microorganisms. In the present work, two antimicrobial soaps were formulated in solid and liquid form using essential oil of Schinus terebinthifolius and Piper nigrun, analysed and compared with other antimicrobial soaps available on the market. In addition, the microbiological safety of the products developed was tested, according to ANVISA criteria. All products developed in this work have microbiological safety, but the best inhibitory results regarding the growth of the microorganisms Staphylococcus aureus and Escherichia coli were obtained with the soaps in liquid form.
Highlights
Bacterial resistance to antimicrobial agents has increased in recent years due to many factors, including the general increase in antibiotic prescriptions
In addition to the compounds that make up essential oils that have antimicrobial activity, it is noted that their volatility and odour can influence the diameter of the inhibitory zones
The products developed in this work are in accordance with RDC 07/2015 (ANVISA, 2015) which deals with the microbiological control of cosmetic products
Summary
Bacterial resistance to antimicrobial agents has increased in recent years due to many factors, including the general increase in antibiotic prescriptions. The use of antiseptic agents for the correct cleaning of human skin is extremely important. According to RDC no 07 of February 2015 in Brazil (ANVISA, 2015), cosmetics, perfumes and personal hygiene products are “preparations made up of natural or synthetic substances, for external use in the different parts of the human body, skin, capillary system, nails, lips, genitals external, teeth and mucous membranes of the oral cavity, with the exclusive or main objective of cleaning, perfuming, altering their appearance and or correcting body odours and either protecting or maintaining them in good condition”. Within the skin care line, disinfectants or antiseptics must have high germicidal efficacy, that is, have a rapid effect, broad antimicrobial spectrum, prolonged action, present chemical stability, in addition to being odourless or having a pleasant odour (Alterthum & Carvalhal, 1999). Microorganisms grow at a pH close to 7, mainly in the range of 6.6 to 7.5, there are some that develop at pH 4 (Gomes, Silva-Mann, Mattos & Rabbani, 2013)
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