Abstract
A new heparinized hydrophilic polymer (Anthron) which contains a large amount of heparin ionically bound to the polymer matrix has been developed. Anthron showed excellent and long-term blood compatibility both in animal and clinical tests. It has been clarified that the long-term blood compatibility of Anthron results from its negative membrane potential and continuous release of heparin from its surface into the blood at the rate of more than 0.01 unit/cm2 min. The application of Anthron for angiographic catheters was studied, and we evaluated the effects of our antithrombogenic angiographic catheter (AAC). As controls, polyurethane catheters (PUC), and polyethylene catheters (PEC), were studied in a similar manner. In addition, the mechanisms of thrombus formation and its complications are discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
