Development of an Integrated Program of Health-Related Quality-of-Life Research for the National Surgical Adjuvant Breast and Bowel Project

Abstract

Abstract : This is the 2nd Year (months 13-24) Report for a Career Development Award for the development of a Health-Related Quality of Life (HRQL) Program for the National Surgical Adjuvant Breast and Bowel Project (NSABP). Specific aims proposed for the award included: (a) Design and implementation of new HRQL components for planned NSABP treatment and prevention trials; (b) testing and implementation of data collection methods to be used in treatment and prevention trials; (c) analysis of HRQL data collected in the NSABP prevention and treatment trials; (d) refinement and extension of HRQL methods to analyze the data from new treatment and prevention studies; (e) enhancement of minority participation in NSABP trials. Primary achievements for the months 13-24 described in this report include: (i) Implementation of two new NSABP protocols with HRQL components (P-2, B-30); (ii) completion of patient recruitment in the first two NSABP treatment protocols with a HRQL component (B-23, C-O6); (iii) conducting successful NSABP HRQL Workshop; (iv) development of real-time monitoring methods to reduce missing data in NSABP HRQL studies; (v) publication of initial quality of life communication from the NSABP P-i protocol; (vi) development of a minority recruitment program for the P-2 (STAR) HRQL component.