Abstract

The main component of a rheographic device at the stage of primary conversion of biosignals is an instrumentation amplifier, the design quality of which determines the main metrological characteristics, the efficiency of the diagnostics, as well as the technical parameters of the diagnostic equipment created on their basis. This article provides an overview of the most well-known fully differential instrumentation amplifier architectures for measuring electrical impedance signals: classical instrumentation amplifier circuit, instrumentation amplifier with cross-connection, instrumentation amplifier with inverting amplifier. To register small changes in electrical impedance signals, high accuracy and low noise in the electrical circuit are required. All circuits were simulated in the LTSpice program. The RMS noise voltage across the 1 Hz to 1 MHz bandwidth was chosen as the main criterion for comparing instrumentation amplifier circuits. Simulation results show that the instrumentation amplifier with inverting amplifier circuit has better noise performance, is compact, 32.2 μV RMS noise. The self-assembly instrumentation amplifier with inverting amplifier is best suited for measuring electrical impedance signals.

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