Abstract

From Challanges in malaria research: Core science and innovation Oxford, UK. 22-24 September 2014

Highlights

  • Dichlorodiphenyltrichloroethane (DDT), pyrethroids, organophosphates and carbamates are insecticides recommended by the World Health Organisation (WHO) for malaria vector control [1]

  • Poor performance of the organophosphate insecticides in the EVA matrix was probably due to the high solubility of these insecticides in this polymer

  • Monofilament polyethylene mesh impregnated with pyrethroid insecticides was successfully produced by a simple direct extrusion technique

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Summary

Background

Dichlorodiphenyltrichloroethane (DDT), pyrethroids, organophosphates and carbamates are insecticides recommended by the World Health Organisation (WHO) for malaria vector control [1]. Long Life Insecticide-Treated Nets (LLIN) and Indoor Residual Spray (IRS) are the flagship interventions recommended by the WHO for malaria control. IRS is most effective when using DDT, a persistent organic pollutant [3]. Insecticide Treated Wall Lining (ITWL) or Netlon® is a slow release technology that combines the advantages of LLIN and IRS. This study explored the effectiveness of inexpensive monofilament mesh linings produced by extruding insecticide impregnated polyethylene and poly(ethyleneco-vinyl acetate) (EVA) directly into a net format. The pyrethroid impregnated mesh samples achieved 100% mortality in this test even after 24 months of storage. Samples impregnated with organophosphates failed to achieve the WHO criterion. Poor performance of the organophosphate insecticides in the EVA matrix was probably due to the high solubility of these insecticides in this polymer

Conclusions
Materials and methods
Results
World Health Organisation
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