Development of an experimental setup for intraoperative angiography system

Abstract

The treatment of locally advanced tumors of the head and neck presents serious difficulties due to the difficulty of localizing growths, namely the proximity to vital organs and systems of the body (brain, large blood vessels) and the small size of the areas of intervention limits the choice of treatment methods. So, the development of helper methods and hardware of intraoperative visualization of blood vessels is relevant. So, the development of auxiliary methods and hardware means of intraoperative blood vessel imaging for objective assessment of adequacy of blood supply and differentiated recognition of anatomical structures is especially relevant in biomedical optics. The aim of the work is to create an experimental setup for the development, testing and modification of the algorithms for improving the quality of the image of blood vessels against the background of surrounding tissues by optical method. The article is devoted to technological and program features of developing and creating an experimental setup for intraoperative imaging. Clinical problem of the necessity of vessel imaging has been established. Current state of intraoperative vessel imaging has been analyzed. Structure of the setup has been determined. The requirements for parts of the setup have been formulated. Usage of the chlorophyll as a new liquid for blood substitution has been experimentally justified. A MATLAB-based model for quality evaluation of functions of the setup has been developed. The experimental results obtained in the article are of great practical importance for the development of a biotechnological system for intraoperative vessel imaging.