Development of an all-in-one percutaneous cardiopulmonary support system.

Abstract

This paper deals with development of an all-in-one percutaneous cardiopulmonary support (PCPS) system. In recent years, PCPS has been used for the treatment of acute myocardial infarction. A prototype of a compact all-in-one PCPS system was developed. The system contains a centrifugal pump and an extra-capillary flow-type membrane lung in one body. The system has a priming volume of 250 ml, which allows for PCPS with no additional blood. The in vitro tests and an ex vivo test were conducted. The system produces 1.6-5 L/min of flow in the experiments. The O2 transfer rate was 310 ml/min, and the CO2 transfer rate was 300 ml/min at a blood flow rate of 5 L/min. This device is compact, requires less priming volume than a standard system, and is easy-to-handle in the experiments. The system is considered applicable to percutaneous cardiopulmonary support.