Abstract

In this work we investigate the design and application of advanced control strategies to a periodic chromatographic process. For the Multicolumn Countercurrent Solvent Gradient Purification process (MCSGP), a nonlinear process described by a periodic profile, we present a step-by-step procedure that enables the seamless development of explicit advanced MPC controllers for such systems. The designed controllers assure optimal operating conditions, periodic input profiles and continuous process monitoring.

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