Abstract
In the course of this study, the expediency of using oil adjuvants as part of an antiviral vaccine was established. The choice of excipients is justified. It was found that as auxiliary substances, the most optimal are TEA, lecithin, oleic acid, mannitol. Stable compositions were obtained using TOTAL oils and base oil. A technology for producing oil adjuvant compositions has been developed. The stability of vaccine preparations with the use of oil adjuvant compositions has been studied. The oil adjuvant is convenient in the production process, as it forms a fairly stable emulsion, the vaccine is freely injected. It was found that the most advantageous physical and technological properties for practical use were the vaccine samples with a volume ratio of antigen and adjuvant 40:60.
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