Development of a Novel Medical Device for Mucositis and Peri-Implantitis Treatment.

Gloria Cosoli,Alfredo De Leo,Lorenzo Scalise,Paola Russo,Gerardo Tricarico,Graziano Cerri,Enrico Primo Tomasini

doi:10.3390/bioengineering7030087

Gloria Cosoli, Alfredo De Leo + Show 5 more

Open Access

https://doi.org/10.3390/bioengineering7030087

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Abstract

In spite of all the developments in dental implantology techniques, peri-implant diseases are frequent (prevalence up to 80% and 56% of subjects for mucositis and peri-implantitis, respectively) and there is an urgency for an effective treatment strategy. This paper presents an innovative electromedical device for the electromagnetic treatment of mucositis and peri-implantitis diseases. This device is also equipped with a measurement part for bioimpedance, which reflects the health conditions of a tissue, thus allowing clinicians to objectively detect impaired areas and to monitor the severity of the disease, evaluate the treatment efficacy, and adjust it accordingly. The design of the device was realized considering literature data, clinical evidence, numerical simulation results, and electromagnetic compatibility (EMC) pre-compliance tests, involving both clinicians and engineers, to better understand all the needs and translate them into design requirements. The reported system is being tested in more than 50 dental offices since 2019, providing efficient treatments for mucositis and peri-implantitis, with success rates of approximately 98% and 80%, respectively.

Highlights

Tooth loss is a very common problem, resulting from disease and trauma [1]; the gold standard choice to replace missing teeth is represented by dental implants, allowing normal function, contour, comfort, and speech, restoring the oral health near to normal limits [2]
The aim of this paper is to present a novel electro-medical device for the treatment of peri-implant diseases, which is currently successfully used for therapy, as well as both the numerical simulations and the electromagnetic compatibility (EMC) pre-compliance tests that the authors performed to obtain useful indications for the optimal design of the device
The developed device is capable of measuring the tissue electrical bioimpedance

Summary

Introduction

Tooth loss is a very common problem, resulting from disease and trauma [1]; the gold standard choice to replace missing teeth is represented by dental implants, allowing normal function, contour, comfort, and speech, restoring the oral health near to normal limits [2]. Surgical treatment of peri-implantitis consists in open debridement (i.e., removal of infected tissue) and decontamination, in order to cure the inflammatory lesion This technique was experimented on animals and humans, but the available evidence is extremely limited [27] and the success rate is not satisfactory. The aim of this paper is to present a novel electro-medical device for the treatment of peri-implant diseases (mucositis and peri-implantitis), which is currently successfully used for therapy, as well as both the numerical simulations and the EMC pre-compliance tests that the authors performed to obtain useful indications for the optimal design of the device.

Safety Aspects

Findings

Discussion and Conclusions