Abstract
A new and efficient manufacturing technology is disclosed in the present work for the preparation of benzoylphenylureas and their key intermediates. This new route significantly reduces the number of reaction steps from six to three, resulting in a streamlined process. Additionally, the overall yield is increased from 56% to over 69%. Compared to the original process route, the new manufacturing route has the advantages of fewer chemical steps, higher overall yield, less process safety hazard and environmental impact. Considering these factors, the new manufacturing route exhibits considerable potential for industrialization.
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