Abstract
This study proposes a new structure for a pressure sensor module that can reduce errors caused by measurement position and direction in noninvasive radial artery pulse wave measurement, which is used for physiological monitoring. We have proposed a structure for a multi-array pressure sensor with a hexagonal arrangement and polydimethylsiloxane that easily fits to the structure of the radial artery, and evaluated the characteristics and pulse wave measurement of the developed sensor by finite element method simulation, a push–pull gauge test, and an actual pulse wave measurement experiment. The developed sensor has a measuring area of 17.6 × 17.6 mm2 and a modular structure with the analog front end embedded on the printed circuit board. The finite element method simulation shows that the developed sensor responds linearly to external pressure. According to the push–pull gauge test results for each channel, there were differences between the channels caused by the unit sensor characteristics and fabrication process. However, the correction formula can minimize the differences and ensure the linearity, and root-mean-squared error is 0.267 kPa in calibrated output. Although additional experiments and considerations on inter-individual differences are required, the results suggested that the proposed multiarray sensor could be used as a radial arterial pulse wave sensor.
Highlights
Blood pressure is one of the important human vital signs and is an important parameter that is always monitored and managed in the clinical setting
We proposed a new multi-channel pressure sensor to improve the accuracy of radial artery pulse wave measurement
For can be attenuated to approximately one-fifth when delivered to the pressure sensor covered by example, if a force of 0.6 N is applied to a jig measuring 3 × 3 mm2, a force of 6.66
Summary
Blood pressure is one of the important human vital signs and is an important parameter that is always monitored and managed in the clinical setting. Blood pressure is defined as the pressure with which blood pushes against the blood vessel wall; it changes with the inflow and outflow of the heart. The blood pressure value changes between the lowest value in ventricular relaxation and the maximum value in ventricular contraction, based on the mean intra-arterial pressure. Blood pressure is generally measured and used as a representative value, such as systolic blood pressure, diastolic blood pressure, mean arterial pressure, and pulse pressure [1]. In order to measure the intermittent blood pressure, a method based on sound or vibration caused by the turbulence generated by occlusion or flow, the blood of the artery is mainly used. To measure blood pressure directly, an invasive catheter embedding a pressure sensor on the tip is generally used through intra-arterial cannulation
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