Development of a Medical Phantom to Evaluate the Function of Low Dose 3D MDCT

Abstract

Background/Objectives: Low dose radiation-based CT imaging is a technology that dramatically improves the information on borders between similar substances but with difference in density. The findings will serve as basic data in developing a CT phantom dedicated for X-ray phase differential imaging.Method/Statistical Analysis: To evaluate the benefits of a phantom for low dose 3D MDCT, SOMATOM Definition AS? (Siemens, Germany) CT scanner that produces 128 slices of images with one rotation was used. The auto-exposure condition (AEC) was applied as it is frequently used in clinical settings for high dose CT. After the image was acquired, a qualitative analysis was conducted to verify the practical use in a clinical setting.Findings: In order to evaluate the images acquired from the in-house produced medical phantom and the resolution in the image space, the phantom must be made of substances that have a similar actual atomic number as water. It is practical to produce the phantom for 3D CT by mixing a pure liquid and powder. The absorption, dispersion and phase differential images acquired through the low dose X-ray device were analyzed on a 5 point Likert scale. The absorption image scored 4.3 points for liquid form and 3.50 points for powder form. Both the dispersion image and the phase differential image scored 3.00 points for the liquid form and 4.50 points for the powder form, indicating that the liquid form produces better quality images in the absorption image, while the powder form produces better images in dispersion or phase differential images. The differences were statistically significant (p<0.05).Improvements/Applications: The findings show that for dispersion and phase differential images, compared to the absorption images, substances in powder form rather than liquid form are conducive to better images. These findings are expected to be of use in the field of medical imaging to produce images with high diagnostic value using low dose radiation.