Abstract
Objectives: TAVI is a well-established alternative to surgical valve replacement. Due to the immense stresses induced to the valves physiological investigations and long lasting durability tests have to be performed prior to certification using pulse-duplicators and high-cyclers. However, there are currently no devices available providing a sterile environment. Therefore, these devices are unsuitable for testing of tissue-engineered (TE) products. The aim of this study was to develop a device that allows the long-term testing of TE heart valves at sterile conditions and provides the capability to measure and control critical parameters.
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