Abstract

A novel 9-borabicyclo[3.3.1]nonane-mediated solid-phase Suzuki coupling was developed to generate dihydrostilbenes (bibenzyls) and related compounds. Using optimized conditions (20 mol% PdCl 2(dppf), 10 equiv. Et 3N, and 10 equiv. olefin/9-BBN, in 9:1 DMF/H 2O, 50°C, 18 h), high conversions to desired products were generally obtained. A small combinatorial library of derivatives was successfully prepared via radiofrequency tagging and directed sorting techniques.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.