Abstract

Recently, development of a human skin equivalent has been under active study. Construction of a human skin equivalent requires co-culturing multiple cell types in a 3D scaffold. The 3D skin equivalent offers advantages over 2D cell culture models, improving the physiological relevance of the model. Combination of microfluidics with 3D skin models have been studied, providing a novel in vitro platform. Here, we examined 3D skin equivalent in a microfluidic chip. Immunohistochemistry and H&E staining revealed that the skin cells proliferated and differentiated in a microfluidic environment. Our study demonstrates successful on-chip culture and differentiation of 3D skin equivalent.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.