Abstract
Ionizing radiation influences animal growth and early development. We have studied bio-effects of low-keV energy argon ion (LKE-AI) using Caenorhabditis elegans focusing on the effects of LKE-AI on larval development. The results showed that LKE-AI of 2–5 keV energy with fluences ranging from 2 × 1014 to 5 × 1014 ions/cm2 induced developmental delay and a decrease in mean brood size, compared to the control group. Under trypan blue staining, some damage to the cuticle was detected. Moreover, C. elegans L1 larvae of hus-1(op241), mek-2(n1989) or sos-1(cs41) deletion mutants showed higher sensitivity to exposure to LKE-AI, and dimethyl sulphoxide could rescue the developmental delay induced by LKE-AI. Our results give an initial insight in the effect of LKE-AI-induced abnormal development via cuticle damage and the generation of reactive oxygen species.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
