Abstract

Introduction Cardiac 31P-MRS is the only non-invasive in vivo technique for the determination of cardiac high energy phosphate metabolism. Changes in cardiac phosphocreatine to adenosine triphosphate ratios (PCr/ATP) occur in common cardiac pathologies and have diagnostic, prognostic and therapeutic utility. However, long acquisition times (20 minutes or more, depending on heart rate) required to achieve sufficient signal to noise ratios for reliable interpretation have limited the clinical utility of 31P-MRS studies in patients with severe cardiac disease.

Highlights

  • Cardiac 31P-MRS is the only non-invasive in vivo technique for the determination of cardiac high energy phosphate metabolism

  • Abstracts of the 13th Annual SCMR Scientific Sessions - 2010 Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-info

  • Long acquisition times (20 minutes or more, depending on heart rate) required to achieve sufficient signal to noise ratios for reliable interpretation have limited the clinical utility of 31P-MRS studies in patients with severe cardiac disease

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Summary

Open Access

Development and validation of a short 31P cardiac magnetic resonance spectroscopy protocol. Abstracts of the 13th Annual SCMR Scientific Sessions - 2010 Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/files/pdf/1532-429X-11-S1-info

Introduction
Protocol development
Results
Conclusion
Full Text
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