Abstract

A 5-years retrospective cohort study was used to review the records or patient files of 1640 HIV patients enrolled between the years 2013-2015. These files were reviewed in 3 HIV treatment Centers (HTCs) which measured a recorded blood pressure routinely.Data was entered in Excel 2010 and analyzed using stata 13. Log rank test and cox proportional hazard regression were used to identify independent risk factors.

Highlights

  • The burden of non-communicable diseases (NCD) and their modifiable risk factors is on the rise in SubSaharan Africa (SSA)

  • These files were reviewed in 3 Human Immunodeficiency Virus (HIV) treatment Centers (HTCs) which measured a recorded blood pressure routinely.Data was entered in Excel 2010 and analyzed using stata 13

  • AIDS: Acquired Immuno-Deficiency Syndrome; area under the curve (AUC): Area Under the Curve; antiretroviral therapy (ART): Anti-retroviral Therapy; COVID-19: Coronavirus Disease 2019; cardiovascular diseases (CVDs): Cardiovascular Diseases; HTCs: HIV Treatment Centers; HIV: Human Immunodeficiency Virus; HTN: Hypertension; LMIC: Lowand Middle Income Countries; NCD: Non-Communicable Disease; negative predictive value (NPV): Negative Predictive Value; positive predictive value (PPV): Positive Predictive Value; PLWH: People Living With HIV; SBP: Systolic Blood Pressure; BMI; Body Mass Index; VL: Viral Load; receiver operating characteristic curve (ROC): Receiver Operating Curve; SWR: South West Region; SSA: Sub-Saharan Africa; UTT; Universal Test and Treat; WHO: World Health Organization

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Summary

Introduction

The burden of non-communicable diseases (NCD) and their modifiable risk factors is on the rise in SubSaharan Africa (SSA). Among people living with HIV (PLHIV), epidemiological studies have revealed a trend of increasing prevalence of four major risk factors of NCDs; hypertension, hyperglycemia, dyslipidemia and obesity [1,2,3]. The increased NCDs risk among PLWH has the potential to threaten the success of ART use, causing morbidity, poor quality of life and premature mortality. In Cameroon, the universal test and treat approach was instituted in 2016 This novel approach requires placing all persons testing positive for HIV on ART irrespective of their immunological and clinical statuses. Since the institution of this novel strategy in Cameroon, very few studies have investigated the epidemiology of NCDs among PLHIV in the context of the universal test and treat strategy. Hypertension has reached epidemic proportion among people living with HIV (PLHIV) and this could have a negative bearing on the quality of life and survival of these patients

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