Development and validation of a finite-element musculoskeletal model incorporating a deformable contact model of the hip joint during gait

Abstract

Musculoskeletal models provide non-invasive and subject-specific biomechanical investigations of the musculoskeletal system. In a musculoskeletal model, muscle forces contribute to the deformation and kinematics of the joint which in turn would alter moment arms of muscles and ground reaction forces and thus affect the prediction of muscle forces and contact forces and contact mechanics of the joint. By far, deformable contact models of the hip have not been considered in musculoskeletal models, and the role of kinematics and deformation within the hip in muscle forces and hip contact mechanics is unknown. In this study, an FE musculoskeletal model including bones, joints and muscles of the lower extremity was developed. A deformable contact model of the hip joint was incorporated and coupled into the musculoskeletal model. Joint angles and ground reaction forces during gait were used as inputs. Optimization minimizing the sum of muscle stresses squared was performed directly to the FE musculoskeletal model in order to simultaneously solve muscle forces and contact forces and contact stresses of the hip joint within a single framework. The calculated hip contact forces corresponded well to the in vivo measurement data. The maximum hip contact stress was 6.5 MPa and occurred at weight-acceptance. The influence of kinematics and deformation in the hip on muscles forces and hip contact forces was minimal and not sensitive to variations in the thickness and properties of the joint cartilage during gait. This suggests that the uncoupled approach in which the hip contact forces and contact mechanics are simulated in separate frameworks would serve as an effective and efficient alternative for subject-specific modelling of the hip. This study provides guidance for the level of complexity needed for future hip models and can be used to evaluate biomechanical changes of the musculoskeletal system following interventions.