Abstract
A capillary electrophoretic method (CE) with ultraviolet absorption detection for ba- clofen in human plasma was developed. The separation was obtained by CE with 50 mM borate buffer at pH 9, followed by detection with an ultraviolet detector at 225 nm. The plasma samples were deproteinized with acetonitrile to remove proteins and to induce sample stacking. With stacking, the limit of detection (LOD) for baclofen in plasma was 0.2 µM. A calibration curve ranging from 1.5 to 300 µM showed to be linear. Both the within-day and day-to-day reproduci- bility and accuracy were less than 15% and 8%, respectively. The recoveries of baclofen in hu- man plasma were 99.6 - 103.3%.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Applied Science and Engineering
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
