Abstract
Neem tree (Azadirachta indica) has a variety of uses in medical traditions due to their antibacterial and anti-inflammatory activities. The way of applications is modernized after centuries and the effectiveness is improved. The use of cosmetics with natural extract is beneficial to lessen the dependence on synthetic products. This study aims to develop natural neem-based lotions with good stability behavior in shelf life. At initial of the research, the neem leaf extract was produced by the Soxhlet extraction method. The synthesized ethanolic neem extract was confirmed by FT-IR and UV–vis analyses. The GC–MS analysis proved the presence of the bioactive compounds in neem extract. A series of neem-based lotions were prepared in stability testing with different formulas by using pure neem leaves extract, diluted neem extract with coconut oil, aloe vera, vitamin E and commercial neem at 25 °C for one year and at 45 °C for three months. All of the prepared lotions exhibited stability at 25 °C where no layer separation and color changes were observed. The moisture became constant after one year of analysis without any formation of granules. The most stable lotion was exhibited by neem-based lotion with coconut oil and aloe vera formula. The sample showed no appearance of layer, no color changed and the moisture remained constant after the testing period at 25 °C and 45 °C.
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