Abstract
ABSTRACT Purpose To develop and assess psychometric properties of a disease-specific quality of life (QOL) assessment tool for patients with chronic uveitis. Methods The initial 42-item chronic uveitis-related QOL questionnaire (CUQOL) was developed by literature review, semi-structured interviews, and expert consultation. Further development and assessment of the CUQOL were performed using Classic Test Theory and Rasch analysis. Results The CUQOL version 1.0 was constructed with 28 items in five dimensions. The five subscales satisfied the requirements of unidimensionality, local independence, and threshold ordering. Cronbach’s α coefficient for overall and each scale of the CUQOL 1.0 ranged from 0.75 to 0.94, with test-retest intraclass correlation ranging from 0.95 to 0.99. The CUQOL 1.0 has satisfactory convergent validity (r = 0.41–0.82), reasonable known group validity (p < .05), and good responsiveness (p < .05). Conclusions The CUQOL 1.0 is reliable and vaild for evaluating the QOL of patients with chronic uveitis.
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