Abstract
The study was conducted to prepare the submicron emulsion gel of tenoxicam to improve the drug loading and permeation of the drug through the skin. The emulsion was prepared using hot homogenization and ultrasonification method. Further sonification was done to obtain the desired size of emulsion. Then by adjusting the concentration of carbopol 947 as 1%, 1.5%, and 2%, the gel was produced from prepared emulsion. The prepared emulgel was evaluated for its pH, viscosity, drug loading, and In vitro drug release studies. The appearance, phase separation, drug entrapment, and globule size of each produced formulation was also evaluated. All submicron emulsion made were consistent, homogenous, and free from phase separation and drug precipitation.
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