Abstract

Permanent Breast Seed Implant (PBSI) is a novel form of breast brachytherapy completed in a single 1-2h procedure. PBSI planning uses CT simulation and treatment involves implanting Pd-103 seeds in and around the breast seroma via needles inserted through a template and guided by free-hand 2D ultrasound. The seroma shape and size vary from CT images to ultrasound and currently neither 3D images nor real-time guidance are available for PBSI. A 3D ultrasound (3DUS) system has been developed to fulfill these needs. This study extends this work to validate the 3DUS clinical implementation in PBSI planning and delivery procedure.

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