Abstract
Developing stem cell-based therapies for neural repair
Highlights
Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression
Significant advances in the area of stem cell biology in the last decade has lead to a special emphasis on the success of stem cell-based applications for the diagnosis and treatment of neurological conditions
Related articles deal with issues including: promoting endogenous neurogenesis, breakthroughs in stem cell differentiation methodologies, using pluripotent and neural stem cells for transplantation, patient derived stem cells for disease modeling and using stem cells for drug discovery
Summary
Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression. The properties of stem cells render them appropriate for endogenous repair, disease modeling, high-throughput drug screening and development as well as neural transplantation procedures. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury.
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