Developing a Beta Cell Vaccine in the Pancreatic Beta Cell Restoring Therapy for Treating Type First Diabetes

Abstract

Gene transfer and biotechnology can develop new beta cells in the human body. Regenerative mechanisms under physiological and pathological conditions, factors involved in stimulation of regeneration, and potential pharmaceutical drugs are discussed. Replication is mediated by mitogenic signaling pathways and upstream activators. These mechanisms also involve upstream activators of mitogenic signaling pathways, including nutrients (glucose, calcium), epidermal and platelet-derived GFs (Glp1, Gip), and hormones (leptin, estrogen, prolactin, and progesterone).