Deuterium-exchange reaction on trimethylamine-borane with sulfonate cation exchanger in the deuterio form

Abstract

The kinetics of H-D exchange on trimethylamino-borane in bi- and triphase systems involving sulfonate cation exchangers in the D + form show that the rate of the isotope exchange is lower in triphase systems in comparison to the liquid-liquid extraction system; nevertheless the yield of the deuterated product in polymeric deuterating systems is essentially much higher than that obtained in applying liquid deuterating agents. The cation-exchange resin when applied in triphase system demonstrates ambivalent behavior, acting as a catalyst toward deuterio-exchange reaction and as a suppressor toward the hydrolysis of TMAB