Abstract
THE heartwood of many conifers and of some broadleaved trees is well protected against attack by fungi and insects by specific and very toxic heartwood-toxins such as pinosylvin, pinosylvin-mono-methylether (PSM), thujaplicins (TH), nootkatin, etc.1. These compounds have proved to be uncoupling toxins which inhibit oxidative phosphorylation in aerobic organisms2. They have in this respect the same effect as the synthetic poisons 2,4-dinitrophenol, pentachlorophenol and other chlorinated phenols which are used for technical impregnation of less-durable timbers and of the sapwood of conifers3. PSM has, besides its main function, a strong activity towards SH-groups of several enzymes4.
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