Determining the effective use of magnetite in lipid-magnetite suspensions

Abstract

Biomagnetic liquids (suspensions) are a colloidal system, consisting of a disperse phase, usually magnetite (Fe 3 O 4 ), surface-active agent (SAA), and disperse medium. Ultra-fine particles of magnetite with biologically-active compounds, immobilized on the surface (e.g., SAA) are of theoretical and practical interest for use in various biotechnologies. Herewith, nanoparticles are investigated as both independent units, and complex organic- inorganic systems “mineral core - functional shell”. These studies are necessary because the structure and morphology of the nanoparticles depend on the functionality of their surface. Biomagnetic liquid (suspension), based on the following components: oil - corn, soybean and sunflower; SAA - monoacylglycerol; magnetite is obtained in our paper. The stability of the suspension is studied by the centrifuge method. The optimum ratio of the lipid-magnetite suspension components - disperse medium (vegetable oil): disperse phase (magnetite): SAA (monoacylglycerol) = 49, 625 g (98, 255 wt. %): 0.35 g (0.7 wt. %): 0.025 g (0.045 wt.%) is determined. Using the infrared spectroscopy method, issues of chemical compatibility of magnetite with the suspension components are investigated. It has been found that there is a chemical interaction (chemisorption) between magnetite and SAA in the suspension. When adding monoacylglycerol to magnetite in the IR-spectrum of SAA there is a new absorption band in the region of the stretching vibrations of associated OH-group at 3375 cm -1 , which can only be attributed to the interaction (“association”) of OH-groups of monoacylglycerol with magnetite (most likely by donor-acceptor mechanism). In addition, during the modification of magnetite by monoacylglycerol, the absorption band of OH-group shifts to the short-wave region 3003 cm -1 (3009 cm -1 in monoacylglycerol), and the bands of symmetric and asymmetric stretching vibrations of COO-group are clearer and shift to long- wave region by approximately 30 cm-1 : ν s = 1760 cm -1 , ν as = 1670 cm -1 (ν s = 1730 cm -1 , ν as = 1640 cm -1 in monoacylglycerol), which may indicate the interaction between the COO-group and magnetite. The importance of the obtained data is that they can be used in obtaining biomagnetic vegetable oil-based liquids. The developed suspensions contain magnetite. And considering the biocompatibility of magnetite with living organisms and its positive effects on the human body, suspensions can be used as food (dietary) additives in food products in order to enrich with digestible iron and create antianemic categories of food products (for treatment and prevention).