Abstract
Purpose: The objective of this study is to determine the anthelmintic activity of Tephrosia spinosa (L.f.) Pers on Indian earth worms. It is a stiffy thorny shrub, commonly found in south India. Methods: Chloroform and methanol extracts of T. spinosa were investigated for anthelmintic activity in Indian earth worms (Pheretima posthuma) using albendazole (10 mg/ml) as standard reference and normal saline as control. The times required to paralyses and kill the worms were calculated. Results: When compared to albendazole, the aerial parts of T. spinosa (L.f.) Pers exhibited significant anthelmintic activity (p<0.001). Conclusion: It is concluded that Tephrosia spinosa has paralytic effect on Indian earth worms.
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