Abstract

The purpose of this study was to determine if high-frequency (HF) ultrasound (20–80 MHz) is sensitive to the change of average human body in temperature (approximately 37 °C) to average room temperatures of approximately 20 °C to 25 °C. When temperatures decrease, water molecules within organic tissue expand, decreasing their density. Changes in temperatures can alter the number of molecules found within a given area, altering tissue density. Two parameters in high-frequency ultrasound (20–80 MHz) have been found to be sensitive to a range of pathologies in resected margins from breast conservation surgery: The number of peaks (the peak density) in the waveform spectrum and the slope of the Fourier transform of the waveform spectrum. Changes in temperatures may affect the accuracy of these two parameters. To test this hypothesis, through-transmission and pulse-echo measurements were acquired fresh (within one hour of slaughter from local butchers) aorta samples from porcine hearts. Results will be presented and discussed. [This work was supported by a Utah Valley University Presidential Fellowship Award.]

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