Abstract
On 01.07.2019, more than 1, 000 children were diagnosed with HIV infection in the Sverdlovsk region. Studies on the prevalence of dermatoses in HIV-positive children indicate a high incidence of viral, fungal and bacterial infections of the skin, compared with HIV-negative children. The skin is the environment in which a diverse community of microorganisms (microbiota) lives. The Global Human Microbiome Project proved the uniqueness of the human microbiome, and suggests to study the effect of human immunity on the formation of microbiome diversity models. The purpose of this study was to assess the incidence of S. aureus, S. spp., C. albicans, C. glabrata, C. krusei, C. tropicalis / C. parapsilosis as a part of skin microbiota in HIV-positive children by polymerase chain reaction.
Highlights
By the beginning of 2018, more than 10 thousand HIV-positive children were registered in the Russian Federation
S. aureus was identified in 4 samples, three of them were obtained from skin lesions
We have found that in HIV-positive children C. krusei, C. tropicalis / C. parapsilosis, resistant to standard antimycotic treatment, and Staphylococcus spp. is persistant
Summary
By the beginning of 2018, more than 10 thousand HIV-positive children were registered in the Russian Federation. By the end of December 2018, 191,882 children from HIV-positive mothers were born in the Russian Federation, 10,822 of them had HIV infection. By July 1, 2019, 1,000 children were diagnosed with HIV infection in the Sverdlovsk Region. Studies of the prevalence of dermatoses in HIV-infected children indicate a high incidence of viral, fungal and bacterial infections of the skin, compared with HIV-negative children [1]. Dias et al (2012) determined the profile of dermatoses in children living with HIV at the Fundação de Medicina Tropical do Amazonas and concluded that children with HIV / AIDS have more non-infectious dermatoses than healthy children. Atopic dermatitis was most often recorded (22.9%) [2]
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