Abstract

The skin of Mangosteen fruit (Garcinia mangostana L.) is widely used as traditional medicine, for it contains a lot of xanthone compounds. Today, there are many products from mangosteen pericarp extract being sold on the market, one of which is the preparation of mangosteen pericarp capsules. Determining the total xanthone content in the preparation of mangosteen pericarp capsules (Garcinia mangostana L.) circulating on the market needs to be done to calculate the levels of xanthone that are not included in the preparation label. The results of the analysis with UV-Visible Spectrophotometry obtains the maximum absorption wavelength at 243 nm and the linear regression equation of the calibration curve that is y=0,0568+0,0727x with a value of r=0,9999. Validation of the analysis method showed the results of intraday precision obtained % RSD 0,34%, 0,17%, and 0,16%, interday precision of 0,23%, 0,35%, and 0,16%. The accuracy obtained was mean % recovery 95,55%, limit of detection 0,35 μg/ml and limit of quantitation 1,15 μg/ml. The results of the determination of the total xanthone content in the mangosteen pericarp capsules were 100,8 μg/mg in sample A; 197 μg/mg in sample B; and 50,2 μg/mg in sample C.

Highlights

  • Health is one of the things that are valuable to everyone's life

  • Analysis Data The total xanthone content in the sample solution was determined by the linear regression equation, y = a + bx from the calibration curve αmangostin

  • Delladari Mayefis descriptively, namely the total xanthone content obtained was made in table form and narrated on the results and discussion and concluded

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Summary

INTRODUCTION

Health is one of the things that are valuable to everyone's life. Various ways will be done by people to be healthy ranging from prevention, health care to treatment of a disease. The most common xanthone compound in the mangosteen fruit peel is α-mangostin. The number of scientific evidence related to the efficacy of mangosteen fruit peel and current technological advances, making the industries both domestic and overseas bring up some preparations from the skin of mangosteen fruit such as a mangosteen fruit tea, leather capsules Mangosteen fruit, mangosteen bark, mangosteen fruit and many more. This circulating Mangosteen skin is claimed to contain efficacious xanthone but the tag does not list the xanthone levels contained in the dosage. One way is Determination of Total Xanthone Content in the Preparation to determine the total xanthone content in the mangosteen pericarp capsule (Garcinia mangostana L.) by the UV-Visible Spectrophotometry method

Methods
AND DISCUSSION
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