Abstract
In this study we report on the comparison between the total selenium in serum (“total Se”) with that which is apparently bound to high molecular weight (>12,000 D) species, presumably proteins (“bound Se”). Nine hundred seventy seven (977) serum samples arising out of a population-based epidemiological study were prepared in duplicate for the determination of “total Se” by pipeting directly into irradiation vials; and separate duplicate aliquots were dialyzed against DI water for the determination of “bound Se”. All samples were analyzed by neutron activation analysis via77mSe (17.4 s). A small dialyzable Se component (∼6%) (“free Se”), defined as the difference between the “total Se” minus the “bound Se”, was identified.
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