Determination of sulfonamides in milk by capillary electrophoresis with PEG@MoS2 as a dispersive solid-phase extraction sorbent.

Jianxin An,Xuan Wang,Nengsheng Ye,Meiting Ming,Jian Li

doi:10.1098/rsos.172104

Abstract

A synthetic polyethylene glycol-molybdenum disulfide (PEG@MoS2) composite was prepared using a simple method, and the application of this material in dispersive solid-phase extraction (DSPE) was investigated for the enrichment of eight sulfonamides (SAs) in milk samples. The composite was characterized by energy dispersive spectroscopy, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy and Brunauer–Emmett–Teller measurements. The results showed that the MoS2 synthesized in the presence of PEG has the advantage of a larger surface area and that the adsorption effect of this MoS2 was enhanced. After extraction, the eight SAs were separated by capillary zone electrophoresis with a good linear relationship (R2 > 0.9902) in the range of 0.3–30 µg ml−1 and good precision (between 0.32% and 9.83%). Additionally, good recoveries (between 60.52% and 110.91%) were obtained for the SAs in the milk samples. The developed PEG@MoS2-based DSPE method could be applied for the enrichment of SAs in real milk samples.

Highlights

MoS2 is a typical transition metal disulfide with a layered structure, in which the molybdenum atoms are sandwiched between two layers of sulfide atoms
The results showed that the MoS2 synthesized in the presence of polyethylene glycol (PEG) has the advantage of a larger surface area and that the adsorption effect of this MoS2 was enhanced
It had been suggested that polyvinyl alcohol can be used to prepare MoS2 nanocomposites to improve their heat and endurance performance [16], and it was suggested that with the help of non-ionic surfactants, such as polyethylene glycol (PEG), MoS2 microspheres were synthesized via a hydrothermal method, and the spheres can adsorb methylene blue and organic pollutants in aqueous solutions [17]

Summary

Introduction

MoS2 is a typical transition metal disulfide with a layered structure, in which the molybdenum atoms are sandwiched between two layers of sulfide atoms. In the field of sample preparation, dahlia-like MoS2 nanostructures can pre-concentrate and extract heavy metals [9]. The MoS2 nanosheets have numerous sulfide atoms on their surfaces and edges, and these sulfide atoms can form complexes with metal ions, allowing them to concentrate and extract the target ion via electrostatic adsorption. It had been suggested that polyvinyl alcohol can be used to prepare MoS2 nanocomposites to improve their heat and endurance performance [16], and it was suggested that with the help of non-ionic surfactants, such as polyethylene glycol (PEG), MoS2 microspheres were synthesized via a hydrothermal method, and the spheres can adsorb methylene blue and organic pollutants in aqueous solutions [17]. Magnetic MoS2-Fe3O4 nanocomposites were synthesized and used for the dispersive solid-phase extraction (DSPE) of Pb (II) and Cu (II) in water and plants [13]

Methods

Results

Conclusion