Abstract
Hemostasis is stopping bleeding in a controlled manner whereas coagulation is a series criterion and to diagnose disorders caused by coagulation in an early period is to determine the coagulation time. These phases are controlled with various tests. In this study, the aim is to determine some coagulation parameters in Sivas Kangal dogs by taking the age and sex into consideration. Coagulation is vitally important in many physiological and pathological cases. The most important tests, complete blood count with peripheral blood smear, prothrombin time (PT), activated partial thromboplastin time (aPTT), and D-dimer fibrin degradation product assay were applied to all subjects, respectively. It was found that thrombocyte counts in Sivas Kangal dogs were affected by the age factor in automatic and manual counting, whereas they were not affected by sex. In the same way, while PT times showed a meaningful change among groups depending on age, aPTT times were not affected by sex or age. The D-dimer assay results, which show the existence of fibrin degradation product, change depending on age and sex.
Highlights
Hemostasis starts with the formation of a blood clot for the repair of the damaged area without forming a pathological clot after the disintegration of vascular integration
Blood clotting starts with thrombocyte plugs formed by active thrombocytes as a result of adhesion and aggregation of active thrombocytes, which are found in blood circulation and are one of the elements of the cellular system
When the platelet count results of the groups obtained from the automatic counting device were compared with the results of manual platelet counting from peripheral smear preparations, the lowest platelet count was recorded in dogs in puberty from both counting methods
Summary
Hemostasis starts with the formation of a blood clot for the repair of the damaged area without forming a pathological clot (thrombosis) after the disintegration of vascular integration. Blood clotting starts with thrombocyte plugs formed by active thrombocytes as a result of adhesion and aggregation of active thrombocytes, which are found in blood circulation and are one of the elements of the cellular system. This process continues with clotting factors in protein using intrinsic, extrinsic, and common paths to form thrombin, which is the most important enzyme in the thrombosis process. Coagulation times vary among individuals depending on the functions of clotting factors playing roles in all processes of coagulation These phases are controlled with various tests just as they are applied to humans [4,5].
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