Abstract
124I has a half-life of 4.2 days, which makes it suitable for imaging over several days along uptake and washout phases. However, it has a low positron branching ratio (23%), because high-energy gamma photons (602 to 1,691 keV), which degrade image quality, are emitted in cascade with positrons. In this study, we measured the single gamma photon fraction of 124I on Inveon PET scanner. Methods: to measure the single gamma photon fraction (SGF) of 124I, we measured the sensitivities of 124I and 18F from energy windows. The spill over ratios (SORs) of 124I were measured to assess the effect of single gamma photons fractions. Results: the SGF were 31%, 24%, and 3% in 0350 ∼ 75, 0350 ∼ 65, and 0350∼ 55 keV, respectively. After single gamma corrections the SOR was decreased by 13% point. Conclusion: the proposed method for measuring the single gamma photons fraction of 124I will be useful to correct the single gamma photons from 124I PET. This information would also be useful to quantify the 124I PET.
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