Determination of Serum 25 (OH) D Concentration in All Study Subjects

Abstract

Background: Various studies reported that Low serum vitamin D has been found to be associated with various types of metabolic illness such as obesity, diabetes mellitus, insulin resistance, cardiovascular diseases including hypertension. Low serum 25 (OH) D levels have been linked to a range of non-skeletal health conditions in adults, including metabolic disorders and cardiovascular diseases. Objective: To determine serum 25 (OH) D concentrations in all study subjects. Methods: This cross-sectional analytical study was carried out to determine serum 25(OH)D concentration in all study subjects. For this study, 90 subjects were recruited after fulfilling the inclusion and exclusion criteria. Study subjects were divided into two groups: 45 subjects with MetS and 45 subjects without MetS. Results: Mean±SD of Age (years), Height (m), Weight (kg), BMI (kg/m2), WC (cm), SBP (mmHg), DBP (mmHg) in Group I and Group II. Subjects with MetS had higher Weight (kg), BMI (kg/m2), WC (cm), SBP (mmHg), DBP (mmHg) than those subjects without MetS. The relationship of BMI, FPG with Vitamin D became significant when FPG entered into model 2. Again, it was evident that Vitamin D was associated with height, BMI and FPG and these relationships remained significant even after TG and HDL-C entered into model 3. Conclusion: In conclusion we can say that low serum vitamin D concentration may predispose to higher BMI, WC, SBP and FPG also low serum vitamin D concentration is negatively correlated with components of MetS (WC, SBP and FPG).