Determination of Sensitivity and Specificity of Cardio-Goniometry in Detection of Coronary Artery Disease in Patients with Osteoporosis and Rheumatoid Arthritis

Abstract

Background: This study aimed to determine the sensitivity and specificity of cardio-goniometry (CGM ) in detection of coronary artery disease in patients with osteoporosis and rheumatoid arthritis that have symptoms of chest pain through angiography or radionuclide myocardial perfusion imaging (MPI). Study Methods and design:100 patients with osteoarthritis and rheumatoid arthritis, according to WHO criteria suspected to have ischemic heart disease enrolled in study. The patients were studied by cardio-goniometry and then the results were compared with angiography or MPI of the same patient (selected as standard diagnosis method). then sensitivity and specificity of cardio-goniometry were calculated. Results: 71 patients underwent to angiography and in 29 patients MPI was done. In first a group 42 patients had Coronary artery disease (CAD). In MPI group 18 patients had CAD in CGM.Seventy-one of these patients underwent angiography for diagnose of ischemic heart disease .29 of them diagnosed as healthy. Of the 100 patients, 29 patients were evaluated previously using MPI to determine ischemic heart disease .11 patients diagnosed as healthy. All 100 patients were examined by cardio-goniometry among which 47 subjects were healthy and the rest subjects had significant and nonsignificant ischemia. Statistical analyses didn’t show significant difference between the results of cardio-goniometry with angiography and myocardial perfusion (p Value >0/05). the results showed the sensitivity and specificity of cardiogoniometry compared rather than angiography and cardiac scan was equal to 0/86 and 0/63. Conclusion: CGM can be suitable for screening of ischemic heart disease in patients with Rheumatoid arthritis and osteoporosis (who cannot do exercise test).