Abstract
Abstract The reaction mixtures of dinucleotides (G3′p5′G and G3′p5′U) with platinum complexes ([Pt(NH3)3Cl]Cl and cis-Pt(NH3)2Cl2) have been treated with exonuclease (snake venom phosphodiesterase and calf spleen phosphodiesterase), and the platinum binding base in dinucleotides has been determined on the basis of HPLC analysis of the enzymatic digestion products.
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