Abstract
After oral application of the central acting analgesic Pentazocine (Fortral R) besides the unchanged drug some further excretion products were detected in human urine by GLC/MS. For their identification E.I. - and C.I. - M.S. as well as the just recently available FAB ( F ast A tom B ombardment)-technique were employed. All analyses were performed on a VG-Micromass 7035; the samples were introduced in the ion source via a fused silica, bonded phase capillary column (30 meters; DB-1 J+W Scientific, Inc.). The analytical profiles of the pure substance and some metabolites are reported as well as the behaviour of the pure substance on acid hydrolysis.
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More From: International Journal of Mass Spectrometry and Ion Physics
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