Abstract
A combination of liquid-liquid extraction (LLE), column chromatography (CC) and gas chromatography-flame ionization detector (GC-FID) were performed to analyze different monolaurin (ML) concentrations in the solution preparations composed of modified coconut oil (MCO). LLE with dichloromethane has been used for the first time to extract ML from solution preparations. The resulting extract was individually purified by CC using silica gel to remove other interfering excipients. ML was detected by TLC and quantified using GC-FID. The combination method is simple and inexpensive and might be used with solution preparations composed of MCO.
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