Abstract

Background: Muscle weakness is a common comorbidity of several severe diseases which results in a reduced independence and quality of life and for the afflicted patients. Patients with rheumatoid arthritis (RA), a disease characterized by a chronic inflammation of the joints, commonly report of muscle weakness as a complication. Muscle weakness is the result of reduced muscle size and intramuscular impairments (i.e., intrinsic muscle dysfunction).

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