Abstract
A rapid and simple HPLC method for the determination of Lovastatin (mevinolin) and mevinolinic acid in fermentation fluids of Aspergillus terreus using a Separon SGX C 18 column and methanol-18 m M orthophosphoric acid (77.5:22.5, v/v) as mobile phase with detection at 238 nm is described. The detection limit of Lovastatin and mevinolinic acid was 20–30 ng/ml.
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