Abstract
We report on a novel nonenzymatic sensor platform for the determination of hydrogen peroxide and glucose. It is based on a carbon paste electrode that was modified with Co0.4Fe0.6LaO3 nanoparticles synthesized by the sol–gel method. The structure and morphology of Co0.4Fe0.6LaO3 nanoparticles were characterized by X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The electrochemical performance of this sensor was evaluated by cyclic voltammetry and amperometry, and the results demonstrated that it exhibits strong electrocatalytical activity towards the oxidation of H2O2 and glucose in an alkaline medium. The sensor has a limit of detection as low as 2.0 nM of H2O2 and a linear range that extends from 0.01 to 800 μM. The response to glucose is characterized by two analytical ranges of different slope, viz. from 0.05 to 5 μM and from 5 to 500 μM, with a 10 nM limit of detection. The glucose sensor has a fast response and good long term stability.
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