Abstract
Asensitive and specific HPLC method for gatifloxacin applicable to serum and urine of volunteers was developed. The method can be operated unattended in over-night runs. It uses reversedphase HPLC with fluorimetric detection. Trovafloxacin serves as internal standard. With a detection limit of 0.03 mgL−1 the method was sensitive enough to measure serum concentrations of gatifloxacin in healthy volunteers for 48 hours after a single oral dose of 400 mg. There was excellent agreement with results obtained by a microbiological assay.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
