Determination of fumonisins in edible vegetable oil by MIL-101(Cr) based dispersive solid-phase extraction combined with high-performance liquid chromatography-tandem mass spectrometry

Abstract

A method was first developed based on MIL-101(Cr) dispersive solid-phase extraction for determining fumonisins in edible vegetable oil. Fumonisins contain hydroxyl and carboxyl groups and were easily adsorbed by MIL-101(Cr) with intermolecular force. With the matrix matching the external standard method for quantification, several extraction factors such as extraction solvent, adsorption dose, extraction time, desorption solvent, desorption solvent volume, desorption time, and filter membrane were optimized. The linear ranges were 5.0–40 μg/L, and the correlation coefficients (r) were greater than 0.9997. The LODs and LOQs of the target analyte were 1.5 and 5.0 μg/kg. At the four spiked concentrations (5, 10, 20, and 40 μg/kg), the recovery rates were between 94.5% and 101.7%, and the RSDs were between 2.02% and 5.32%. The inter-day and intra-day tests recoveries were 98.5%− 99.9% and 93.7%− 98.7%, respectively. The precision of the inter-day and intra-day analysis was 5.09–6.05% and 2.56%− 3.19%, respectively. The pretreatment time of this method is only 1 h, and the efficiency is 4–8 times higher than that of other methods.These results showed that the method was fast, selective, low cost, and sensitive and had obvious advantages for accurately determining and analyzing fumonisins in edible oil samples.