Determination of concentration and enantiomeric excess of amines and amino alcohols with a chiral nickel(ii) complex

Abstract

A chiral N,N'-dioxide-Ni(II) complex was found to exhibit highly enantioselective fluorescent recognition of chiral amines and amino alcohols. It can be used to determine their concentration and ee value. Using a 96-well plate, high-throughput screening for enantiomer discrimination was accomplished.